Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445645 | 0.85 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL7434185 | 0.85 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL7448695 | 0.85 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL7439753 | 0.81 | NPY4R (0.48) | GNPATEPHX2NPY4RNPY1RNPY2R | |
| SCHEMBL7443489 | 0.81 | NPY4R (0.48) | GNPATEPHX2NPY4RNPY1RNPY2R | |
| Trifluoroacetic Acid SCHEMBL9614812 | 0.81 | ITGB1 (0.37) | EPHX2NPY4R | |
| SCHEMBL30798042 | 0.79 | GNPAT (0.49) | GNPATFOLH1NPY4RNPY1RNPY2R | |
| SCHEMBL29628247 | 0.79 | GNPAT (0.49) | GNPATFOLH1NPY4RNPY1RNPY2R | |
| SCHEMBL31232977 | 0.78 | GNPAT (0.51) | GNPATFOLH1NPY4RNPY1RSIRT5 | |
| SCHEMBL30099629 | 0.78 | NPY4R (0.48) | GNPATFOLH1NPY4RNPY1RSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |