Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449366 | 1.00 | MAPT (0.71) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL7461552 | 1.00 | MAPT (0.71) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL6752273 | 0.88 | MAPT (0.71) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL6752264 | 0.88 | MAPT (0.71) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL6750795 | 0.88 | MAPT (0.71) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL6750794 | 0.88 | MAPT (0.71) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL9664895 | 0.88 | MAPT (0.78) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL6939775 | 0.85 | MAPT (0.70) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL6944234 | 0.85 | MAPT (0.70) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL8445710 | 0.85 | MAPT (0.70) | MAPTALDH1A1GAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077976-B1 | WATER SOLUBLE AZOLES AS BROAD-SPECTRUM ANTIFUNGALS | JANSSEN PHARMACEUTICA NV (BE) | 2002-08-07 | — | — | EP | disclosed |
| US-6384030-B1 | COMPOUNDS AS FUNGICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-05-07 | — | — | US | disclosed |
| EP-1077976-A1 | WATER SOLUBLE AZOLES AS BROAD-SPECTRUM ANTIFUNGALS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058530-A1 | WATER SOLUBLE AZOLES AS BROAD-SPECTRUM ANTIFUNGALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-11-18 | — | — | WO | disclosed |