Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.57 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486989 | 1.00 | F10 (0.57) | F10DEGS1ALOX5APFEN1NAMPT | |
| SCHEMBL7449386 | 1.00 | F10 (0.57) | F10DEGS1ALOX5APFEN1NAMPT | |
| SCHEMBL7452368 | 0.89 | F10 (0.59) | F10ALOX5APFEN1NAMPTPRSS1 | |
| SCHEMBL7448455 | 0.89 | F10 (0.59) | F10ALOX5APFEN1NAMPT | |
| SCHEMBL7680057 | 0.89 | F10 (0.59) | F10ALOX5APFEN1NAMPTPRSS1 | |
| SCHEMBL7448459 | 0.89 | F10 (0.59) | F10ALOX5APFEN1NAMPT | |
| SCHEMBL7452359 | 0.89 | F10 (0.59) | F10ALOX5APFEN1NAMPTPRSS1 | |
| SCHEMBL7489382 | 0.89 | F10 (0.59) | F10ALOX5APFEN1NAMPT | |
| SCHEMBL7453902 | 0.86 | F10 (0.60) | F10ALOX5APFEN1NAMPTPRSS1 | |
| SCHEMBL7453911 | 0.86 | F10 (0.60) | F10ALOX5APFEN1NAMPTPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1189879-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1183234-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| EP-1159264-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000071512-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000071509-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |