SCHEMBL7449704

SCHEMBL7449704

FC(F)(F)CC1=NNc2ccccc2C=C1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9934042 0.77 GAA (0.43) GAAMAPT
SCHEMBL11710279 0.77 GAA (0.43) GAAMAPT
SCHEMBL8696697 0.77 GAA (0.43) GAAMAPT
SCHEMBL8552747 0.77 GAA (0.43) GAAMAPT
SCHEMBL7492328 0.73 GAA (0.39) GAAMAPT
SCHEMBL4717203 0.72 GAA (0.38) GAAMAPT
SCHEMBL4481007 0.72 MAPT (0.42) GAAMAPT
SCHEMBL4903371 0.71 GAA (0.41) GAAMAPT
SCHEMBL8197993 0.71 MAPT (0.37) GAAMAPT
SCHEMBL10650119 0.71 GAA (0.37) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047608-A1 Method of Treatment and Pharmaceutical Composition for Morning Hypertension Dharma Laboratories LLC (US) 2022-02-17 US disclosed
US-20020151543-A1 Compositions and methods employing R (-) fluoxetine and other active ingredients SEPRACOR INC. 2002-10-17 US disclosed
WO-2000024399-A1 COMPOSITIONS AND METHODS EMPLOYING R(-) FLUOXETINE AND OTHER ACTIVE INGREDIENTS SEPRACOR INC. (US) 2000-05-04 WO disclosed
WO-1999061014-A2 COMPOSITIONS AND METHODS EMPLOYING R(-) FLUOXETINE AND OTHER ACTIVE INGREDIENTS SEPRACOR INC. (US) 1999-12-02 WO disclosed