Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308928 | 1.00 | PRSS1 (0.51) | PRSS1TMPRSS15DPP4DPP7HDAC8 | |
| SCHEMBL7450368 | 1.00 | PRSS1 (0.51) | PRSS1TMPRSS15DPP4DPP7HDAC8 | |
| Hydrochloric Acid SCHEMBL4970030 | 0.99 | PRSS1 (0.50) | PRSS1TMPRSS15DPP4DPP7HDAC8 | |
| Hydrochloric Acid SCHEMBL7307256 | 0.99 | PRSS1 (0.50) | PRSS1TMPRSS15DPP4DPP7HDAC8 | |
| SCHEMBL23211353 | 0.81 | DPP7 (0.56) | DPP4DPP7HDAC8DPP8 | |
| SCHEMBL18492863 | 0.81 | DPP4 (0.62) | DPP4DPP7HDAC8DPP8 | |
| SCHEMBL23211354 | 0.81 | DPP7 (0.56) | DPP4DPP7HDAC8DPP8 | |
| SCHEMBL1039399 | 0.81 | HDAC8 (0.68) | DPP4DPP7HDAC8DPP8 | |
| SCHEMBL8077871 | 0.81 | HDAC8 (0.68) | DPP4DPP7HDAC8DPP8 | |
| SCHEMBL14390395 | 0.81 | HDAC8 (0.67) | DPP4DPP7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725797-B1 | BIVALENT THROMBIN INHIBITORS | CA NAT RESEARCH COUNCIL (CA) | 2001-01-10 | — | — | EP | disclosed |
| EP-0725797-A1 | BIVALENT THROMBIN INHIBITORS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1996-08-14 | — | — | EP | disclosed |
| EP-0513543-B1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE AG (DE) | 1995-10-25 | — | — | EP | disclosed |
| WO-1995011921-A1 | BIVALENT THROMBIN INHIBITORS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1995-05-04 | — | — | WO | disclosed |
| EP-0513543-A1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-11-19 | — | — | EP | disclosed |