Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.39 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | CYBB | P04839 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 6/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PROC | P04070 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7214094 | 0.89 | F10 (0.40) | F10GPR6F2C1SPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7214007 | 0.84 | F2 (0.38) | F10GPR6CYBBNCF1F2 | |
| Trifluoroacetic Acid SCHEMBL7452864 | 0.83 | F10 (0.48) | F10F2PLGPROCHDAC1 | |
| Trifluoroacetic Acid SCHEMBL7213069 | 0.83 | F10 (0.36) | F10GPR6CYBBNCF1F2 | |
| Trifluoroacetic Acid SCHEMBL7213074 | 0.83 | GPR6 (0.35) | F10GPR6CYBBNCF1F2 | |
| SCHEMBL7452877 | 0.82 | HDAC1 (0.35) | F10F2PRSS1PLGPROC | |
| Trifluoroacetic Acid SCHEMBL7417460 | 0.76 | F10 (0.60) | F10F2PRSS1PLGPROC | |
| Trifluoroacetic Acid SCHEMBL7450568 | 0.74 | F10 (0.52) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL7452358 | 0.74 | F10 (0.40) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL7457704 | 0.74 | F10 (0.52) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001039759-A2 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |