Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.53 |
| ▸ | ESR1 | P03372 | 14/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451351 | 0.91 | F2 (0.58) | F2ESR1ESR2MLNRABCB11 | |
| SCHEMBL7442171 | 0.83 | ESR1 (0.59) | F2ESR1ESR2 | |
| SCHEMBL7438768 | 0.82 | F2 (0.71) | F2ESR1ESR2 | |
| SCHEMBL7452312 | 0.82 | F2 (0.62) | F2ESR1ESR2MLNRABCB11 | |
| SCHEMBL7452879 | 0.81 | F2 (0.52) | F2HRH3 | |
| SCHEMBL7574644 | 0.81 | ESR1 (0.67) | ESR1ESR2MLNRABCB11NR3C1 | |
| SCHEMBL6954751 | 0.81 | F2 (0.55) | F2ESR1ESR2MLNRABCB11 | |
| SCHEMBL6967074 | 0.80 | F2 (0.56) | F2ESR1ESR2MLNRABCB11 | |
| SCHEMBL7452204 | 0.79 | HRH3 (0.55) | F2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL7439386 | 0.79 | F2 (0.67) | F2ESR1ESR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |