Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954207 | 1.00 | HDAC6 (0.41) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL7452547 | 0.79 | HDAC6 (0.44) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL7448926 | 0.79 | HDAC6 (0.44) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL8449238 | 0.79 | HDAC6 (0.44) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL7452553 | 0.79 | HDAC6 (0.44) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL7448936 | 0.79 | HDAC6 (0.44) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL14138147 | 0.75 | HDAC6 (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL7799930 | 0.74 | ADORA2A (0.53) | — | |
| SCHEMBL8446161 | 0.74 | KDM4E (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9230518 | 0.72 | KDM4E (0.45) | HDAC6KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941993-B1 | Process for purifying 2-amino-6-chloro-9-[(1'S,2'R)-1',2'-bis(hydroxymethyl)cyclopropane-1'-yl]methylpurine | AJINOMOTO KK (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-6172224-B1 | Process for isolating 2-amino-6-chloro-9-[(1'S,2'R)-1'2'-bis(hydroxymethyl)-cyclopropane-1'-YL]methylpurine and an optical isomer thereof | AJINOMOTO CO., INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0941993-A1 | Process for purifying 2-amino-6-chloro-9-[(1'S,2'R)-1',2'-bis(hydroxymethyl)cyclopropane-1'-yl]methylpurine | Ajinomoto Co., Ltd. (JP) | 1999-09-15 | — | — | EP | disclosed |