Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444230 | 0.96 | EDNRB (0.90) | EDNRBEDNRA | |
| SCHEMBL7451079 | 0.92 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8860870 | 0.89 | EDNRB (0.82) | EDNRBEDNRA | |
| SCHEMBL7446711 | 0.86 | EDNRB (0.90) | EDNRBEDNRA | |
| SCHEMBL7437354 | 0.83 | EDNRB (0.89) | EDNRBEDNRA | |
| SCHEMBL7450437 | 0.83 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL27508609 | 0.83 | EDNRB (0.85) | EDNRBEDNRA | |
| SCHEMBL7450477 | 0.83 | EDNRB (0.85) | EDNRBEDNRA | |
| SCHEMBL7450209 | 0.83 | EDNRB (0.59) | EDNRBEDNRA | |
| SCHEMBL7446500 | 0.82 | EDNRB (1.00) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | claimed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | claimed |
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | disclosed |