Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | KLK1 | P06870 | 5/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7445570 | 0.99 | F2 (0.48) | F2F10KLK1KLK5PRSS1 | |
| Hydrochloric Acid SCHEMBL7440222 | 0.95 | F2 (0.47) | F2F10KLK1KLK5PRSS1 | |
| SCHEMBL6457217 | 0.93 | F2 (0.56) | F2F10KLK1KLK5PRSS1 | |
| Hydrochloric Acid SCHEMBL7448447 | 0.92 | F2 (0.56) | F2F10KLK1KLK5PRSS1 | |
| Hydrochloric Acid SCHEMBL7451035 | 0.92 | F2 (0.56) | F2F10KLK1KLK5PRSS1 | |
| Hydrochloric Acid SCHEMBL7451053 | 0.88 | F2 (0.42) | F2F10KLK1KLK5PRSS1 | |
| SCHEMBL7424418 | 0.86 | F2 (0.44) | F2F10KLK1KLK5PRSS1 | |
| SCHEMBL7442305 | 0.86 | F2 (0.48) | F2F10KLK1KLK5PRSS1 | |
| Hydrochloric Acid SCHEMBL7446389 | 0.86 | F2 (0.44) | F2F10KLK1KLK5PRSS1 | |
| Hydrochloric Acid SCHEMBL7449029 | 0.86 | F2 (0.47) | F2F10KLK1KLK5PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | claimed |
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |