Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978605 | 0.89 | HPGD (0.77) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL2436680 | 0.84 | HPGD (0.65) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL2436689 | 0.84 | HPGD (0.65) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL7456162 | 0.83 | KDM4E (0.68) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL2435315 | 0.83 | HPGD (0.71) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL7242265 | 0.82 | HPGD (0.73) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL14409571 | 0.78 | TSHR (0.70) | HPGDALDH1A1POLBTSHRGLA | |
| SCHEMBL6271671 | 0.77 | HPGD (0.77) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL192942 | 0.77 | HPGD (0.77) | HPGDALDH1A1POLBSMN1; SMN2ADRB2 | |
| SCHEMBL12504031 | 0.77 | HPGD (0.77) | HPGDALDH1A1POLBSMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189883-A2 | SUBSTITUTED PYRROLIDINES AS CELL ADHESION INHIBITORS | Aventis Pharma Limited (GB) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000068195-A2 | SUBSTITUTED PYRROLIDINES AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 2000-11-16 | — | — | WO | disclosed |