Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.87 |
| ▸ | F10 | P00742 | 1/20 | 0.66 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452930 | 0.93 | F2 (0.94) | F2F10NR4A2PRSS1 | |
| SCHEMBL7448763 | 0.90 | F2 (0.85) | F2F10PRSS1 | |
| SCHEMBL7450283 | 0.90 | F2 (0.91) | F2F10PRSS1 | |
| SCHEMBL7447051 | 0.89 | F2 (0.89) | F2F10PRSS1 | |
| SCHEMBL7450042 | 0.89 | F2 (0.83) | F2F10PRSS1 | |
| SCHEMBL7448742 | 0.87 | F2 (0.80) | F2F10PRSS1 | |
| SCHEMBL7455175 | 0.87 | F2 (0.84) | F2F10 | |
| Hydrochloric Acid SCHEMBL34433766 | 0.86 | F2 (1.00) | F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL28553434 | 0.86 | F2 (1.00) | F2F10PRSS1 | |
| SCHEMBL7450261 | 0.85 | F2 (0.72) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214291-A1 | BIPHENYL DERIVATIVES USED AS NHE-3 INHIBITORS | MERCK PATENT GmbH (DE) | 2002-06-19 | — | — | EP | disclosed |
| US-6380430-B1 | ANTICOAGULANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTERHAFTUNG (DE) | 2002-04-30 | — | — | US | disclosed |
| WO-2001021582-A1 | BIPHENYL DERIVATIVES USED AS NHE-3 INHIBITORS | MERCK PATENT GMBH (DE) | 2001-03-29 | — | — | WO | disclosed |
| EP-1076643-A1 | BIPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999057096-A1 | BIPHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-11-11 | — | — | WO | disclosed |