Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305572 | 0.98 | TSHR (0.46) | MAPTTSHRMEN1KMT2AGAA | |
| SCHEMBL22014309 | 0.89 | TSHR (0.50) | MAPTTSHRMEN1KMT2AGAA | |
| SCHEMBL13631583 | 0.82 | TSHR (0.43) | TSHRPPARDTDP1TP53ALDH1A1 | |
| SCHEMBL11032582 | 0.80 | TSHR (0.50) | TSHRMEN1KMT2AGAAPPARD | |
| SCHEMBL7456931 | 0.80 | TSHR (0.41) | TSHRPPARDTDP1TP53ALDH1A1 | |
| SCHEMBL7505873 | 0.80 | TSHR (0.41) | TSHRMEN1KMT2APPARDTDP1 | |
| SCHEMBL1418450 | 0.80 | TSHR (0.41) | TSHRMEN1KMT2APPARDTDP1 | |
| SCHEMBL11138865 | 0.80 | GAA (0.46) | MAPTTSHRMEN1KMT2AGAA | |
| SCHEMBL13992767 | 0.79 | CXCR4 (0.46) | TSHRMEN1KMT2APPARDTDP1 | |
| SCHEMBL24462561 | 0.79 | PPARD (0.42) | MAPTTSHRMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |