Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451566 | 0.94 | HTT (0.58) | HTTCA1CA2CA7CA9 | |
| SCHEMBL7447542 | 0.90 | HTT (0.45) | HTTCA1CA2CA7CA9 | |
| SCHEMBL10564679 | 0.87 | HTT (0.54) | HTTCA1CA2CA7CA9 | |
| SCHEMBL13595480 | 0.87 | HTT (0.54) | HTTCA1CA2CA7CA9 | |
| SCHEMBL1987154 | 0.87 | HTT (0.54) | HTTCA1CA2CA7CA9 | |
| SCHEMBL7448869 | 0.86 | HTT (0.50) | HTTCA1CA2CA7CA9 | |
| SCHEMBL7976000 | 0.86 | HTT (0.50) | HTTKMT2A | |
| SCHEMBL7451964 | 0.84 | HTT (0.48) | HTTCA1CA2CA7CA9 | |
| SCHEMBL12050573 | 0.83 | MEN1 (0.39) | HTTKMT2AMEN1MAPK1 | |
| SCHEMBL7456495 | 0.82 | HTT (0.36) | HTTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |