Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | AKT1 | P31749 | 5/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6774861 | 0.99 | KDR (0.42) | KDRAKT1KCNQ3KCNQ2CDK2 | |
| SCHEMBL5756624 | 0.90 | KDR (0.54) | KDRAKT1 | |
| Hydrochloric Acid SCHEMBL7558014 | 0.85 | AKT1 (0.42) | KDRAKT1CDK2 | |
| SCHEMBL5760397 | 0.84 | MEN1 (0.56) | KDRAKT1 | |
| SCHEMBL7377861 | 0.81 | RXFP2 (0.45) | KDRAKT1CDK2 | |
| Ammonia Solution, Strong SCHEMBL7446734 | 0.80 | AKT1 (0.43) | AKT1CDK2 | |
| Hydrochloric Acid SCHEMBL7443795 | 0.77 | CNR1 (0.43) | AKT1CDK2 | |
| Hydrochloric Acid SCHEMBL7455665 | 0.74 | AKT1 (0.47) | AKT1CDK2 | |
| SCHEMBL6415440 | 0.73 | F10 (0.49) | AKT1 | |
| SCHEMBL5760425 | 0.72 | KDR (0.39) | KDRAKT1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |