⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160878 | 0.72 | — | — | |
| SCHEMBL7692384 | 0.72 | — | — | |
| SCHEMBL7695281 | 0.72 | — | — | |
| SCHEMBL2629416 | 0.72 | — | — | |
| SCHEMBL29959076 | 0.72 | — | — | |
| SCHEMBL13521785 | 0.72 | — | — | |
| SCHEMBL2045260 | 0.72 | — | — | |
| SCHEMBL2045262 | 0.72 | — | — | |
| SCHEMBL13771795 | 0.67 | — | — | |
| SCHEMBL2651405 | 0.67 | HSP90AA1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104801345-A | Supported type mercury-free catalyst for chloroethylene production with acetylene hydrochlorination method | XINJIANG CORPS MODERN GREEN CHLOR ALKALI CHEMICAL ENGINEERING RES CT CO LTD | 2015-07-29 | — | — | CN | claimed |
| JP-6025193-A | — | — | None | — | — | JP | disclosed |
| JP-9151122-A | — | — | None | — | — | JP | disclosed |
| EP-3002280-B1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIV GREENWICH (GB) | 2023-05-24 | — | — | EP | disclosed |
| US-11622937-B2 | Polyphenolic polymer to make water-insoluble molecules become water-soluble | SINGH MEWA (US) | 2023-04-11 | — | — | US | disclosed |
| CN-110072521-B | Pharmaceutical combination comprising a T-type calcium channel blocker | 爱杜西亚药品有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-109415352-B | 3-amino-1, 2, 4-triazine derivatives and their use for controlling unwanted plant growth | 拜耳作物科学股份公司 | 2022-04-26 | — | — | CN | disclosed |
| EP-3002280-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | University of Greenwich (GB) | 2016-04-06 | — | — | EP | disclosed |
| EP-2229371-B1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIV GREENWICH (GB) | 2015-12-23 | — | — | EP | disclosed |
| EP-2430003-A1 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | Nektar Therapeutics (US) | 2012-03-21 | — | — | EP | disclosed |
| US-20040092536-A1 | Neurologically active compounds and compounds with multiple activities | NAFTCHI N ERIC (US) | 2004-05-13 | — | — | US | disclosed |
| WO-2004026845-A1 | NEW PROCESS FOR THE SYNTHESIS OF HIGH PURITY 3,5-DIAMINO-6-(2, 3-DICHLOROPHENYL)-1,2,4-TRIAZINE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2004-04-01 | — | — | WO | disclosed |
| US-6413962-B1 | ANESTHESIA AND TEMPERATURES REDUCTION; ALPHA-ADRENOCEPTOR AGONIST; RESTORATIVE TO CENTRAL NERVOUS SYSTEM, ESPECIALLY MOTOR AND SENSORY FUNCTIONAL LOSSES FROM TRAMATIC SPINAL CORD INJURIES; ANTISPASTICS; NONSEDATIVE; SIDE EFFECT REDUCTION | NAFTCHI N ERIC (US) | 2002-07-02 | — | — | US | disclosed |
| US-5958933-A | HAVING A GUANIDINO GROUP ALIPHATICALLY LINKED TO A XANTHINE GROUP, ADRENERGIC STIMULANTS | NAFTCHI N ERIC (US) | 1999-09-28 | — | — | US | disclosed |
| JP-H09151122-A | HAIR DYEING COMPOSITION | LION CORP | 1997-06-10 | — | — | JP | disclosed |
| JP-H0625193-A | COMPOUND HAVING PHARMACOLOGIC ACTIVITY TO CENTRAL NERVOUS SYSTEM | WELLCOME FOUND LTD:THE | 1994-02-01 | — | — | JP | disclosed |
| US-5128216-A | LUBRICANTS FOR MAGNETIC MEDIA | DIGITAL EQUIPMENT CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0464991-A2 | Lubricants for magnetic media | QUANTUM CORPORATION (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0021120-B1 | 3,5-DIAMINO-1,2,4-TRIAZINE DERIVATIVES, PROCESS FOR PREPARING SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-04-06 | — | — | EP | disclosed |
| EP-0021120-A1 | 3,5-Diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-07 | — | — | EP | disclosed |