Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.47 |
| ▸ | CTRC | Q99895 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553101 | 0.82 | F2 (0.49) | F2CTRCHTR6F10PRSS2 | |
| SCHEMBL7445442 | 0.81 | F2 (0.52) | F2CTRCF10PRSS2 | |
| Hydrochloric Acid SCHEMBL6553096 | 0.81 | F2 (0.48) | F2CTRCHTR6F10PRSS2 | |
| SCHEMBL7451365 | 0.81 | F2 (0.67) | F2CTRCHTR6F10PRSS2 | |
| SCHEMBL7496894 | 0.78 | SLC6A2 (0.50) | F2CTRCHTR6F10PRSS2 | |
| Hydrochloric Acid SCHEMBL7496883 | 0.77 | SLC6A2 (0.49) | F2CTRCHTR6F10PRSS2 | |
| SCHEMBL7451490 | 0.77 | F2 (0.70) | F2CTRCHTR6F10PRSS2 | |
| SCHEMBL6553019 | 0.76 | F2 (0.73) | F2CTRCF10PRSS2 | |
| Hydrochloric Acid SCHEMBL7451487 | 0.76 | F2 (0.69) | F2CTRCHTR6F10PRSS2 | |
| SCHEMBL7435999 | 0.75 | F2 (0.51) | F2CTRCHTR6F10PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-B1 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |