SCHEMBL7451901

SCHEMBL7451901

COc1ccc2c(c1)C(=O)c1cc(OC)ccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA4 P22748 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
PTPN1 P18031 1/20 0.56
ALDH1A1 P00352 3/20 0.55
LCK P06239 2/20 0.54
METAP1 P53582 2/20 0.53
USP8 P40818 2/20 0.53
IDO1 P14902 2/20 0.53
PRKACA P17612 1/20 0.53
PRKACG P22612 1/20 0.53
PRKACB P22694 1/20 0.53
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2252533 1.00 CA1 (0.57) CA1CA2CA4CA7CA9
SCHEMBL10885799 0.96 CA1 (0.53) CA1CA2CA4CA7CA9
SCHEMBL8076766 0.95 CA1 (0.57) CA1CA2CA4CA7CA9
SCHEMBL7786812 0.95 CA1 (0.57) CA1CA2CA4CA7CA9
SCHEMBL30629120 0.95 CA1 (0.57) CA1CA2CA4CA7CA9
2-Methoxyanthraquinone SCHEMBL222927 0.94 PTPN1 (0.60) CA1CA2CA4CA7CA9
SCHEMBL4645032 0.92 PTPN1 (0.58) CA1CA2CA4CA7CA9
SCHEMBL2993382 0.91 CA1 (0.53) CA1CA2CA4CA7CA9
SCHEMBL23111388 0.91 CA1 (0.57) CA1CA2CA4CA7CA9
SCHEMBL28155812 0.91 CA1 (0.57) CA1CA2CA4CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163372-A4 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES PRINCETON SEPARATIONS (US) 2002-10-02 EP claimed
EP-1163372-A1 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES Princeton Separations (US) 2001-12-19 EP claimed
WO-2000056933-A1 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES PRINCETON SEPARATIONS (US) 2000-09-28 WO claimed
EP-3801507-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2021-04-14 EP disclosed
EP-1163372-A4 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES PRINCETON SEPARATIONS (US) 2002-10-02 EP disclosed
EP-1163372-A1 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES Princeton Separations (US) 2001-12-19 EP disclosed
WO-2000056933-A1 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES PRINCETON SEPARATIONS (US) 2000-09-28 WO disclosed