Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423342 | 0.91 | MAPK9 (0.54) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2422573 | 0.88 | MAPK9 (0.51) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2420814 | 0.87 | MAPK9 (0.51) | MAPK9MAPK10LMNAKMT2AMEN1 | |
| SCHEMBL7440721 | 0.86 | MAPK9 (0.49) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2425741 | 0.83 | MAPK9 (0.59) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2422247 | 0.82 | MAPK9 (0.54) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2424569 | 0.81 | MAPK9 (0.56) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1518747 | 0.81 | MAPK9 (0.56) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2426328 | 0.81 | MAPT (0.46) | MAPK9MAPK10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2424312 | 0.81 | MAPK9 (0.55) | MAPK9MAPK10MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |