Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.74 |
| ▸ | F2 | P00734 | 17/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7453855 | 0.91 | F10 (0.76) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7455024 | 0.89 | F10 (0.73) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7451754 | 0.87 | F10 (0.70) | F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7361309 | 0.85 | F10 (0.98) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7458596 | 0.84 | F2 (0.75) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7451177 | 0.84 | F10 (0.66) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7365691 | 0.84 | F10 (0.86) | F10F2PRSS1 | |
| SCHEMBL8343396 | 0.82 | F10 (0.84) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7367577 | 0.82 | F2 (0.75) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8345837 | 0.82 | F10 (0.86) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |