Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL7632619 | 0.88 | TSHR (0.54) | TSHRTHRBSMN1; SMN2AKR1B1LMNA | |
| Heptane SCHEMBL8517437 | 0.85 | TSHR (0.61) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| Octane SCHEMBL9403184 | 0.85 | TSHR (0.61) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| Heptane SCHEMBL8697580 | 0.85 | TSHR (0.61) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| Hexane SCHEMBL11235960 | 0.83 | TSHR (0.70) | TSHRTHRBSMN1; SMN2AKR1B1LMNA | |
| Hexane SCHEMBL11134445 | 0.83 | — | — | |
| Methacrylic Acid SCHEMBL1140479 | 0.81 | TSHR (0.52) | TSHRTHRBAKR1B1ALDH1A1HSD17B10 | |
| Methacrylic Acid SCHEMBL4642347 | 0.81 | TSHR (0.52) | TSHRTHRBAKR1B1ALDH1A1HSD17B10 | |
| Pentane SCHEMBL9570503 | 0.80 | — | — | |
| Decane SCHEMBL11227696 | 0.79 | TSHR (0.80) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806958-A4 | INHIBITION OF PLATELET BINDING | PRP INC (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-0806958-A1 | INHIBITION OF PLATELET BINDING | PRP, INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996003136-A1 | INHIBITION OF PLATELET BINDING | PRP, INC. (US) | 1996-02-08 | — | — | WO | disclosed |
| US-5462752-A | Administering platelet binding-site agent | PRP, INC. (US) | 1995-10-31 | — | — | US | disclosed |