Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447784 | 0.81 | — | — | |
| SCHEMBL7447043 | 0.81 | SLC6A4 (0.35) | SLC6A4DRD2 | |
| SCHEMBL7446759 | 0.81 | DRD3 (0.38) | HTR1ASIGMAR1SLC6A4DRD2 | |
| SCHEMBL7449308 | 0.79 | DRD3 (0.42) | HTR1ADRD2 | |
| SCHEMBL7448567 | 0.77 | — | — | |
| SCHEMBL7446300 | 0.75 | DRD3 (0.41) | HTR1ADRD2 | |
| SCHEMBL10934615 | 0.74 | — | — | |
| SCHEMBL26294726 | 0.72 | KDM1A (0.35) | KDM1A | |
| SCHEMBL7450002 | 0.72 | KDM1A (0.42) | KDM1A | |
| SCHEMBL121088 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006536-A1 | HEXAHYDRO-NAPHTHALENONE OXIMES AND HYDRAZONES | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |