Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 11/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14737623 | 0.87 | CA1 (0.46) | CA1CA7CA2CTSKCYP2D6 | |
| SCHEMBL5447582 | 0.79 | CA1 (0.47) | CA1CA7CA2CTSKCYP2D6 | |
| SCHEMBL14923588 | 0.78 | CA1 (0.46) | CA1CA7CA12CA14CA2 | |
| SCHEMBL12915836 | 0.78 | CA1 (0.46) | CA1CA7CA12CA14CA2 | |
| SCHEMBL16232686 | 0.78 | CA1 (0.46) | CA1CA7CA12CA14CA2 | |
| SCHEMBL5873409 | 0.78 | CA1 (0.46) | CA1CA7CA2CTSKCYP2D6 | |
| SCHEMBL5433610 | 0.78 | CA1 (0.46) | CA1CA7CA2CTSKCYP2D6 | |
| SCHEMBL6632972 | 0.76 | CA1 (0.47) | CA1CA7CA12CA14CA2 | |
| SCHEMBL768534 | 0.76 | CA1 (0.47) | CA1CA7CA12CA14CA2 | |
| SCHEMBL2386106 | 0.76 | CA1 (0.47) | CA1CA7CA12CA14CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051176-A4 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARM PROD INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1051176-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037304-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-07-29 | — | — | WO | disclosed |