Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 3/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455269 | 1.00 | TSHR (0.61) | TSHRFAAHTRPV1EP300TOP1 | |
| SCHEMBL28901846 | 0.92 | TSHR (0.58) | TSHRFAAHTRPV1EP300LSS | |
| SCHEMBL2411571 | 0.90 | TSHR (0.58) | TSHRFAAHTRPV1EP300TOP1 | |
| SCHEMBL2417497 | 0.90 | TSHR (0.58) | TSHRFAAHTRPV1EP300TOP1 | |
| SCHEMBL2411575 | 0.90 | TSHR (0.58) | TSHRFAAHTRPV1EP300TOP1 | |
| SCHEMBL6711719 | 0.86 | TSHR (0.52) | TSHRFAAHTRPV1TOP1LSS | |
| SCHEMBL6711721 | 0.86 | TSHR (0.52) | TSHRFAAHTRPV1TOP1LSS | |
| SCHEMBL9545718 | 0.86 | EP300 (0.48) | FAAHEP300TOP1LSSTERT | |
| SCHEMBL9545687 | 0.86 | EP300 (0.48) | FAAHEP300TOP1LSSTERT | |
| SCHEMBL9545730 | 0.86 | EP300 (0.48) | FAAHEP300TOP1LSSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889945-B1 | FRAGRANT MACROCYCLIC LACTONES | FIRMENICH & CIE (CH) | 2002-12-04 | — | — | EP | disclosed |
| US-RE36493-E | Fragrant macrocyclic lactones | FIRMENICH SA (CH) | 2000-01-11 | — | — | US | disclosed |
| US-5792740-A | PERFUMES; MUSKY ODORS | FIRMENICH SA (CH) | 1998-08-11 | — | — | US | disclosed |