Octane

Octane

SCHEMBL7455677

CCCCCCCC.CN(C)O

nearest known ligand 0.61

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
THRB P10828 1/20 0.61
DNM1 Q05193 3/20 0.56
SLC22A1 O15245 3/20 0.53
LMNA P02545 2/20 0.53
ALDH1A1 P00352 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
HIF1A Q16665 1/20 0.50
SLC22A2 O15244 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexadecane SCHEMBL9330341 1.00 TSHR (0.61) TSHRTHRBDNM1SLC22A1LMNA
Dodecane SCHEMBL6806149 1.00 TSHR (0.61) TSHRTHRBDNM1SLC22A1LMNA
Hexane SCHEMBL272768 0.96 TSHR (0.54) TSHRTHRBDNM1SLC22A1LMNA
Decane SCHEMBL28596369 0.84 TSHR (0.73) TSHRTHRBDNM1SLC22A1LMNA
Octane SCHEMBL639577 0.84 TSHR (0.73) TSHRTHRBDNM1SLC22A1LMNA
Decane SCHEMBL738409 0.84 TSHR (0.73) TSHRTHRBDNM1SLC22A1LMNA
Octane SCHEMBL28596371 0.84 TSHR (0.73) TSHRTHRBDNM1SLC22A1LMNA
Hexadecane SCHEMBL738410 0.84 TSHR (0.73) TSHRTHRBDNM1SLC22A1LMNA
Dodecane SCHEMBL4314349 0.84 TSHR (0.73) TSHRTHRBDNM1SLC22A1LMNA
Trimethylammonium SCHEMBL18106783 0.84 TSHR (0.73) TSHRTHRBDNM1SLC22A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0668271-B1 Process for the preparation of isocyanurate-group containing polyisocyanates BASF AG (DE) 2002-01-16 EP disclosed
US-5489663-A TRIMERIZING ALIPHATIC AND/OR CYCLOALIPHATIC DIISOCYANATES USING TETRAALKYLAMMONIUM ALKYL CARBONATE OR MIXTURES WITH QUATERNARY AMMONIOALKYL CARBONATE CATALYSTS, DEACTIVATING CATALYST BASF AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed
EP-0668271-A1 Process for the preparation of isocyanurate-group containing polyisocyanates BASF Aktiengesellschaft (DE) 1995-08-23 EP disclosed
EP-0400435-B1 Carbonic half-ester of betaine structure BASF AG (DE) 1994-04-13 EP disclosed
EP-0400435-A2 Carbonic half-ester of betaine structure BASF Aktiengesellschaft (DE) 1990-12-05 EP disclosed