Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233396 | 0.71 | KDM4E (0.36) | ABL1RIN1TDP1ALDH1A1KDM4E | |
| SCHEMBL9629117 | 0.69 | ABL1 (0.47) | ABL1RIN1TDP1ELANEGSK3A | |
| SCHEMBL11024134 | 0.68 | GAA (0.46) | ABL1RIN1TDP1ALDH1A1KMT2A | |
| SCHEMBL6233301 | 0.68 | GAA (0.46) | ABL1RIN1TDP1ALDH1A1KMT2A | |
| SCHEMBL15129469 | 0.67 | ABL1 (0.48) | ABL1RIN1TDP1ELANEGSK3A | |
| SCHEMBL10756511 | 0.66 | ABL1 (0.47) | ABL1RIN1TDP1ELANEGSK3A | |
| SCHEMBL11555998 | 0.66 | ABL1 (0.50) | ABL1RIN1TDP1ELANEGSK3A | |
| SCHEMBL6235119 | 0.66 | GBA1 (0.53) | ABL1RIN1TDP1KDM4E | |
| SCHEMBL6098531 | 0.66 | ELANE (0.57) | ABL1RIN1TDP1ELANEGSK3A | |
| SCHEMBL6231243 | 0.66 | GBA1 (0.53) | ABL1RIN1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718290-B1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-5912261-A | ANTIDIABETIC AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| EP-0718290-A1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |