Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.56 |
| ▸ | NPY4R | P50391 | 3/20 | 0.52 |
| ▸ | NPY1R | P25929 | 2/20 | 0.52 |
| ▸ | NPY2R | P49146 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 9/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456632 | 1.00 | TFPI (0.56) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29993768 | 0.96 | NPY4R (0.55) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29993329 | 0.96 | NPY4R (0.55) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29398068 | 0.93 | NPY4R (0.53) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30571144 | 0.92 | TFPI (0.62) | TFPIKISS1RBACE1 | |
| SCHEMBL11247622 | 0.92 | NPY4R (0.59) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30887551 | 0.92 | TFPI (0.45) | TFPINPY4RNPY1RNPY2RNPY5R | |
| Acetic Acid SCHEMBL11118747 | 0.90 | NPY4R (0.58) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL9551261 | 0.90 | BACE1 (0.55) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL30880856 | 0.90 | TFPI (0.67) | TFPINPY4RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065398-A1 | Genetically engineered immunoglobulins for use as tools in human therapeutics | CENTRO DE INMUNOLOGIA MOLECULAR (CU) | 2002-05-30 | — | — | US | disclosed |
| US-5891996-A | WITH NON-HUMAN VARIABLE REGIONS AND HUMAN CONSTANT REGIONS; LESS IMMUNOGENIC WITH IMPROVED EFFECTOR FUNCTIONS; ANTITUMOR AGENTS; FOR DIAGNOSITIC IMAGING AND MONITORING | CENTRO DE INMUNOLOGIA MOLECULAR (CU) | 1999-04-06 | — | — | US | disclosed |