Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 12/20 | 0.70 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.43 |
| ▸ | PLG | P00747 | 4/20 | 0.41 |
| ▸ | KLK1 | P06870 | 3/20 | 0.41 |
| ▸ | PLAT | P00750 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7333225 | 0.91 | PLAU (0.73) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7345791 | 0.91 | PLAU (0.84) | PLAUF2PRSS1PLGKLK1 | |
| SCHEMBL7333232 | 0.87 | PLAU (0.70) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7337301 | 0.86 | PLAU (0.64) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7344757 | 0.84 | PLAU (0.62) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7339921 | 0.81 | PLAU (0.57) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7339090 | 0.80 | PLAU (0.57) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7337885 | 0.80 | PLAU (0.55) | PLAUF2PRSS1PLGKLK1 | |
| Trifluoroacetic Acid SCHEMBL7592047 | 0.80 | PLAU (0.56) | PLAUF2PRSS1PLGKLK1 | |
| SCHEMBL7334984 | 0.79 | PLAU (0.65) | PLAUF2PRSS1PLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000018-A2 | UROKINASE INHIBITORS | Abbott Laboratories (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005096-A2 | UROKINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1999-02-04 | — | — | WO | disclosed |