Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 19/20 | 0.62 |
| ▸ | CDK2 | P24941 | 19/20 | 0.62 |
| ▸ | CCNE2 | O96020 | 18/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 16/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.58 |
| ▸ | CDK9 | P50750 | 3/20 | 0.58 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | CDK7 | P50613 | 1/20 | 0.56 |
| ▸ | CCNH | P51946 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192607 | 1.00 | CCNE1 (0.62) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL5627261 | 0.99 | CDK2 (0.63) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL5193721 | 0.92 | CDK2 (0.60) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL5193714 | 0.92 | CDK2 (0.60) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL5626690 | 0.91 | CDK2 (0.60) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL5626684 | 0.91 | CDK2 (0.60) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6817978 | 0.87 | CCNE1 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6817973 | 0.87 | CCNE1 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6821676 | 0.86 | CDK2 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6821675 | 0.86 | CDK2 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183256-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071543-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-11-30 | — | — | WO | disclosed |