⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28210 | 0.78 | — | — | |
| SCHEMBL15892148 | 0.72 | — | — | |
| SCHEMBL15892153 | 0.69 | — | — | |
| SCHEMBL5986420 | 0.69 | — | — | |
| SCHEMBL5884978 | 0.69 | — | — | |
| SCHEMBL2627779 | 0.67 | — | — | |
| SCHEMBL25946788 | 0.67 | — | — | |
| SCHEMBL113046 | 0.67 | — | — | |
| SCHEMBL2627772 | 0.67 | — | — | |
| SCHEMBL17488427 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184219-C | Taxusane phosphonic oxygen methyl ether derivant | BRISTOL MYERS SQUIBB CO (US) | 2005-01-12 | — | — | CN | disclosed |
| US-6455575-B2 | ANTITUMOR AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| EP-0639577-B1 | Phosphonooxymethyl or methylthiomethyl ethers of taxane derivatives as antitumor agents | BRISTOL MYERS SQUIBB CO (US) | 2002-05-15 | — | — | EP | disclosed |
| US-20010023255-A1 | PHOSPHONOOXYMETHYL ETHERS OF TAXANE DERIVATIVES | GOLIK JERZY (US) | 2001-09-20 | — | — | US | disclosed |
| EP-0604910-B1 | Phosphonooxymethyl ethers of taxane derivatives | BRISTOL MYERS SQUIBB CO (US) | 2000-06-14 | — | — | EP | disclosed |
| CN-1037774-C | Phosphonooxymethyl ether derivatives of taxanes | BRISTOL MYERS SQUIBB CO (US) | 1998-03-18 | — | — | CN | disclosed |
| US-5646176-A | Phosphonooxymethyl ethers of taxane derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0639577-A1 | Phosphonooxymethyl or methylthiomethyl ethers of taxane derivatives as antitumor agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |
| CN-1093369-A | Phosphonooxymethyl ether derivatives of taxanes | BRISTOL MYERS SQUIBB CO (US) | 1994-10-12 | — | — | CN | disclosed |
| EP-0604910-A1 | Phosphonooxymethyl ethers of taxane derivatives | Bristol-Myers Squibb Company (US) | 1994-07-06 | — | — | EP | disclosed |