Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078873 | 1.00 | BAZ2B (0.33) | BAZ2BHTR2ANR2E1 | |
| SCHEMBL6078880 | 1.00 | BAZ2B (0.33) | BAZ2BHTR2ANR2E1 | |
| SCHEMBL6079019 | 0.87 | CNR1 (0.33) | — | |
| SCHEMBL6079028 | 0.87 | CNR1 (0.33) | — | |
| SCHEMBL6079217 | 0.87 | — | — | |
| SCHEMBL6079212 | 0.87 | — | — | |
| SCHEMBL6078450 | 0.86 | — | — | |
| SCHEMBL6078446 | 0.86 | — | — | |
| SCHEMBL6079047 | 0.84 | GRN (0.35) | — | |
| SCHEMBL6079042 | 0.84 | GRN (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725783-B1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-12-18 | — | — | EP | disclosed |
| US-5612477-A | 2-(pyrazol-3-yl)carbapenem derivatives | SMITHKLINE BEECHAM P.L.C | 1997-03-18 | — | — | US | disclosed |