SCHEMBL7459344

SCHEMBL7459344

CCCCCCCC[Si](CCCCCCCC)(CCCCCCCC)O[SiH2]O[SiH3]

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29190444 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL7907071 0.89 TSHR (0.40) TSHRTHRB
SCHEMBL9003878 0.88
SCHEMBL28904431 0.83 TSHR (0.32) TSHRTHRB
SCHEMBL28702309 0.83 TSHR (0.32) TSHRTHRB
SCHEMBL28720214 0.83 TSHR (0.32) TSHRTHRB
SCHEMBL9545970 0.79 TSHR (0.32) TSHRTHRB
SCHEMBL10723520 0.74 TSHR (0.35) TSHRTHRB
SCHEMBL29444098 0.74
SCHEMBL2122895 0.72 TSHR (0.42) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006988-A4 HIGH PURITY BRANCHED ALKYLSILSESQUIOXANE FLUIDS CLARIANT LSM ITALIA SPA (US) 2002-01-30 EP disclosed
EP-1006988-A1 HIGH PURITY BRANCHED ALKYLSILSESQUIOXANE FLUIDS ARCHIMICA (FLORIDA), Inc. (US) 2000-06-14 EP disclosed
WO-1999002123-A1 HIGH PURITY BRANCHED ALKYLSILSESQUIOXANE FLUIDS ARCHIMICA (FLORIDA) INC. (US) 1999-01-21 WO disclosed