SCHEMBL7459385

SCHEMBL7459385

C=CCCCCCCCCCCCCCCCCC1=C(CCCCCC)CC1

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
ALDH1A1 P00352 2/20 0.50
SCD O00767 1/20 0.39
TDP1 Q9NUW8 2/20 0.37
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37
LMNA P02545 1/20 0.36
ALOX15 P16050 1/20 0.35
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2019543 0.96 TSHR (0.58) TSHRALDH1A1SCDTDP1USP2
SCHEMBL2016082 0.88 TSHR (0.46) TSHRALDH1A1TDP1USP2HPGD
SCHEMBL3944934 0.83 TSHR (0.48) TSHRALDH1A1THRATHRB
SCHEMBL2335039 0.80 SCD (0.46) TSHRALDH1A1SCDLMNATHRB
SCHEMBL23539923 0.80 TSHR (1.00) TSHRALDH1A1THRB
SCHEMBL11900218 0.80 TSHR (1.00) TSHRALDH1A1THRB
SCHEMBL1548257 0.80 TSHR (1.00) TSHRALDH1A1THRB
SCHEMBL22322880 0.80 TSHR (1.00) TSHRALDH1A1THRB
SCHEMBL22164116 0.80 TSHR (1.00) TSHRALDH1A1THRB
SCHEMBL7153127 0.80 TSHR (1.00) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020072561-A1 OLEFIN-BASED COPOLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-13 US disclosed