SCHEMBL7459482

SCHEMBL7459482

CCOC(=O)CNC(=O)N1CCC(CC(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)(c2ccccc2)c2ccccc2)CC1NC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 16/20 0.52
CCR3 P51677 16/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7466987 0.86 CCR1 (0.59) CCR1CCR3
SCHEMBL8891368 0.81 CCR3 (0.57) CCR1CCR3
Hydrochloric Acid SCHEMBL7464931 0.79 CCR1 (0.56) CCR1CCR3
SCHEMBL7459475 0.78 CCR3 (0.55) CCR1CCR3
SCHEMBL7459470 0.78 CCR3 (0.79) CCR1CCR3
SCHEMBL7467269 0.78 CCR3 (0.68) CCR1CCR3
Hydrochloric Acid SCHEMBL7467259 0.77 CCR3 (0.67) CCR1CCR3
Hydrochloric Acid SCHEMBL7465922 0.77 CCR3 (0.62) CCR1CCR3
SCHEMBL7460099 0.76 CCR3 (0.72) CCR1CCR3
Hydrochloric Acid SCHEMBL7467013 0.76 CCR3 (0.60) CCR1CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1219294-A1 MELANIN CONCENTRATING HORMONE ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-03 EP disclosed