Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9888690 | 0.83 | EHMT2 (0.56) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| SCHEMBL30495965 | 0.83 | EHMT2 (0.56) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| SCHEMBL7818128 | 0.79 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| SCHEMBL9967715 | 0.79 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| SCHEMBL5061383 | 0.79 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| SCHEMBL30358632 | 0.79 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17633942 | 0.78 | EHMT2 (0.50) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10706712 | 0.78 | EHMT2 (0.50) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| SCHEMBL7245352 | 0.76 | EHMT2 (0.48) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 | |
| SCHEMBL256693 | 0.76 | EHMT2 (0.48) | EHMT2EHMT1APOBEC3GHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025227-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-04-12 | — | — | WO | disclosed |