Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.82 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7466646 | 0.95 | MCHR1 (0.81) | MCHR1CHRM4SIGMAR1CCR3HTR2A | |
| SCHEMBL7459555 | 0.92 | MCHR1 (0.86) | MCHR1CHRM4SIGMAR1CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7466901 | 0.91 | MCHR1 (0.85) | MCHR1CHRM4SIGMAR1CCR3CCR1 | |
| SCHEMBL7463098 | 0.91 | MCHR1 (1.00) | MCHR1SIGMAR1CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7463694 | 0.90 | MCHR1 (0.98) | MCHR1SIGMAR1CCR3CCR1 | |
| SCHEMBL7466099 | 0.89 | MCHR1 (0.85) | MCHR1CCR3CCR1DRD2 | |
| SCHEMBL7469192 | 0.86 | MCHR1 (0.79) | MCHR1SIGMAR1CCR3CCR1DRD2 | |
| SCHEMBL7458837 | 0.86 | MCHR1 (0.85) | MCHR1CHRM4CCR3CCR1DRD2 | |
| Hydrochloric Acid SCHEMBL7467690 | 0.85 | MCHR1 (0.83) | MCHR1CHRM4SIGMAR1CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7465351 | 0.85 | MCHR1 (0.83) | MCHR1CHRM4CCR3CCR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |