Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27828837 | 0.96 | — | — | |
| SCHEMBL5574 | 0.95 | — | — | |
| SCHEMBL28129545 | 0.95 | CYP2D6 (0.54) | CYP2D6TAAR1KDM4EGRM4SLC6A2 | |
| SCHEMBL4284210 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL7805756 | 0.91 | — | — | |
| SCHEMBL23304291 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL7741978 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL3062035 | 0.91 | — | — | |
| Methane SCHEMBL18173817 | 0.91 | — | — | |
| SCHEMBL28172438 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839125-A4 | NOVEL CATIONIC LIPIDS AND THE USE THEREOF | IMARX PHARMACEUTICAL CORP (US) | 2002-10-30 | — | — | EP | disclosed |
| CN-1082043-C | Novel cationic lipids and the use thereof | IMARX PHARMACEUTICAL CORP (US) | 2002-04-03 | — | — | CN | disclosed |
| EP-0839125-A1 | NOVEL CATIONIC LIPIDS AND THE USE THEREOF | IMARX PHARMACEUTICAL CORP. (US) | 1998-05-06 | — | — | EP | disclosed |
| CN-1177342-A | Novel cationic lipids and the use thereof | IMAR PHARMACEUTICAL CORP (US) | 1998-03-25 | — | — | CN | disclosed |
| WO-1996026179-A1 | NOVEL CATIONIC LIPIDS AND THE USE THEREOF | IMARX PHARMACEUTICAL CORP. (US) | 1996-08-29 | — | — | WO | disclosed |