Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 14/20 | 0.45 |
| ▸ | FNTB | P49356 | 13/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | NRAS | P01111 | 1/20 | 0.36 |
| ▸ | HRAS | P01112 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502102 | 0.94 | FNTA (0.45) | FNTAPGGT1BFNTBKCNH2DRD2 | |
| SCHEMBL3518400 | 0.84 | FNTA (0.47) | FNTAPGGT1BFNTBKCNH2DRD2 | |
| SCHEMBL7665099 | 0.80 | FNTA (0.52) | FNTAPGGT1BFNTBKCNH2NRAS | |
| SCHEMBL3501573 | 0.80 | FNTA (0.70) | FNTAPGGT1BFNTBNRASHRAS | |
| Hydrochloric Acid SCHEMBL8088734 | 0.80 | FNTA (0.51) | FNTAPGGT1BFNTBKCNH2NRAS | |
| SCHEMBL3502103 | 0.80 | FNTA (0.45) | FNTAPGGT1BFNTBKCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL7192628 | 0.79 | FNTA (0.70) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL7665102 | 0.75 | FNTA (0.39) | FNTAPGGT1BFNTBKCNH2DRD2 | |
| SCHEMBL5547981 | 0.75 | FNTA (0.40) | FNTAPGGT1BFNTBKCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL7657378 | 0.74 | FNTA (0.72) | FNTAPGGT1BFNTBNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019529-A4 | A METHOD OF TREATING CANCER | MERCK & CO INC (US) | 2002-09-11 | — | — | EP | claimed |
| JP-2001518281-A | — | — | 2001-10-16 | — | — | JP | claimed |
| EP-1019529-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-1009854-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1999010525-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | claimed |
| WO-1999010523-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | claimed |
| EP-1019529-A4 | A METHOD OF TREATING CANCER | MERCK & CO INC (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1019529-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-2000016626-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999010525-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |