SCHEMBL7461588

SCHEMBL7461588

CC1=Cc2c(CCc3cc4c(c5c3C=C(C)C5)CCCC4)cc3c(c2C1)CCCC3

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
GNG2 P59768 1/20 0.31
GNB1 P62873 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2960799 0.78 MEN1 (0.31) MEN1KMT2A
SCHEMBL7455540 0.73 MAPT (0.41) MAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL7460267 0.73
SCHEMBL2963965 0.71 MEN1 (0.31) MEN1KMT2A
SCHEMBL7459707 0.69
SCHEMBL7451719 0.69
SCHEMBL2960447 0.68 MEN1 (0.31) MEN1KMT2A
SCHEMBL5716704 0.66 CES1 (0.41) MAPTMEN1KMT2A
SCHEMBL7464131 0.66
SCHEMBL2961701 0.64 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6369254-B1 COORDINATION CATALYST FOR POLYMERIZATION CATALYSTS BASELL TECHNOLOGY COMPANY BV (NL) 2002-04-09 US disclosed
EP-0846122-B1 BRIDGED METALLOCENE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY BV (NL) 2000-07-05 EP disclosed