SCHEMBL7461972

SCHEMBL7461972

NC(=O)CC[C@H](N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.55
PTGS1 P23219 1/20 0.48
GSTK1 Q9Y2Q3 1/20 0.48
RIMKLA Q8IXN7 1/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.46
KMT2A Q03164 2/20 0.45
ALOX15 P16050 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
DPP4 P27487 2/20 0.44
DPP8 Q6V1X1 2/20 0.44
DPP9 Q86TI2 2/20 0.44
GRM8 O00222 1/20 0.42
GRM6 O15303 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GSR P00390 1/20 0.42
CYP1A2 P05177 1/20 0.42
GRIK1 P39086 1/20 0.42
GRM5 P41594 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30198445 1.00 FOLH1 (0.55) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6810612 1.00 FOLH1 (0.55) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6810621 1.00 FOLH1 (0.55) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6809811 0.99 FOLH1 (0.54) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6809803 0.99 FOLH1 (0.54) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL30792478 0.96 FOLH1 (0.54) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6809847 0.96 KMT2A (0.49) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6809858 0.96 KMT2A (0.49) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6806102 0.94 KMT2A (0.47) FOLH1PTGS1GSTK1RIMKLANAALAD2
SCHEMBL6806093 0.94 KMT2A (0.47) FOLH1PTGS1GSTK1RIMKLANAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179055-A1 NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2002-02-13 EP claimed
WO-2000071695-A1 NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-11-30 WO claimed
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-11-06 US disclosed
EP-4448544-A2 CARBONIC ANHYDRASE IX LIGANDS 3B Pharmaceuticals GmbH (DE) 2024-10-23 EP disclosed
WO-2023111350-A2 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS CA9, CA13, CA4 FOLH1 36/4885PTGS1 3908/4885GSTK1 4732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.