Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.67 |
| ▸ | CCR3 | P51677 | 14/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.52 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7461449 | 0.99 | CCR1 (0.66) | CCR1CCR3MEN1ALDH1A1LMNA | |
| SCHEMBL7470954 | 0.90 | CCR3 (0.61) | CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7461078 | 0.89 | CCR3 (0.60) | CCR1CCR3 | |
| SCHEMBL7461534 | 0.87 | CCR1 (0.64) | CCR1CCR3 | |
| SCHEMBL7464621 | 0.87 | CCR3 (0.72) | CCR1CCR3 | |
| SCHEMBL7460163 | 0.87 | CCR3 (0.66) | CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7459913 | 0.87 | CCR1 (0.63) | CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7470140 | 0.87 | CCR3 (0.71) | CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7461977 | 0.86 | CCR3 (0.65) | CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL8892059 | 0.83 | CCR3 (0.66) | CCR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |