Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 7/20 | 0.39 |
| ▸ | CCR3 | P51677 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7465687 | 0.99 | MCHR1 (0.52) | MCHR1CHRM4CCR5CCR3CCR1 | |
| SCHEMBL7463105 | 0.89 | MCHR1 (0.65) | MCHR1CCR5CCR3CCR1 | |
| SCHEMBL7459761 | 0.89 | MCHR1 (0.51) | MCHR1CHRM4CCR5CACNA1GKCNH2 | |
| Hydrochloric Acid SCHEMBL7463703 | 0.89 | MCHR1 (0.64) | MCHR1CCR5CCR3 | |
| Hydrochloric Acid SCHEMBL7462023 | 0.88 | MCHR1 (0.51) | MCHR1CHRM4CCR5CACNA1GKCNH2 | |
| Hydrochloric Acid SCHEMBL7461507 | 0.88 | MCHR1 (0.58) | MCHR1CHRM4CCR5CCR3CCR1 | |
| SCHEMBL7463862 | 0.88 | MCHR1 (0.42) | MCHR1CHRM4CCR3CCR1OPRL1 | |
| SCHEMBL7458844 | 0.87 | MCHR1 (0.56) | MCHR1CHRM4CCR5CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7455711 | 0.87 | MCHR1 (0.47) | MCHR1CCR5CCR3 | |
| Hydrochloric Acid SCHEMBL7465359 | 0.86 | MCHR1 (0.56) | MCHR1CHRM4CCR5CCR3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |