SCHEMBL7463344

SCHEMBL7463344

Cc1ccccc1B(OC(C)C)c1ccccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ACHE P22303 2/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
ESR1 P03372 1/20 0.35
SCN4A P35499 9/20 0.34
CYP3A4 P08684 3/20 0.34
LMNA P02545 2/20 0.34
SCN1A P35498 2/20 0.34
SCN5A Q14524 2/20 0.34
SCN9A Q15858 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
NFKB1 P19838 2/20 0.34
SCN8A Q9UQD0 2/20 0.34
SLC6A4 P31645 2/20 0.34
CYP2C9 P11712 1/20 0.34
KCNK3 O14649 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7181071 0.77 TSHR (0.45) TSHRACHECA1CA2CA7
SCHEMBL28994175 0.75 TSHR (0.43) TSHRACHECA1CA2CA7
O-Xylene SCHEMBL7221582 0.71 TSHR (0.59) TSHRACHECA1CA2CA7
SCHEMBL7461066 0.70 ORAI1 (0.52) TSHRCA7CYP3A4LMNACYP1A2
SCHEMBL28994183 0.70 TSHR (0.38) TSHRACHECA1CA2CA7
SCHEMBL126881 0.68 TSHR (0.53) TSHRACHECA1CA2CA7
Ammonia Solution, Strong SCHEMBL11227356 0.66 TSHR (0.50) TSHRACHECA1CA2CA7
SCHEMBL187525 0.66 TSHR (0.50) TSHRACHECA1CA2CA7
SCHEMBL21318192 0.66 TSHR (0.50) TSHRACHECA1CA2CA7
SCHEMBL29392408 0.66 TSHR (0.50) TSHRACHECA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775706-B1 Borates photoinitiators from polyboranes CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
EP-1203999-A2 Photoinitiator comprising a borane and an electron donating compound Ciba SC Holding AG (CH) 2002-05-08 EP disclosed
US-6057078-A PHOTOGRAPHY CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
US-5807905-A POLYMERIZATION OF UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
EP-0775706-A2 Borates photoinitiators from polyboranes Ciba SC Holding AG (CH) 1997-05-28 EP disclosed