Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462598 | 0.90 | NT5E (0.34) | — | |
| SCHEMBL7459896 | 0.88 | PTGER1 (0.33) | TP53 | |
| SCHEMBL7467857 | 0.88 | TP53 (0.31) | TP53 | |
| SCHEMBL7454567 | 0.87 | TP53 (0.31) | TP53 | |
| SCHEMBL7462604 | 0.87 | ESR1 (0.30) | — | |
| SCHEMBL6777028 | 0.86 | TP53 (0.30) | TP53 | |
| SCHEMBL7462607 | 0.86 | MAPT (0.30) | — | |
| SCHEMBL6772344 | 0.85 | — | — | |
| SCHEMBL7456814 | 0.85 | PPARD (0.36) | — | |
| SCHEMBL7462945 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |