Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457561 | 0.94 | RXFP1 (0.31) | ALDH1A1HPGDTSHRNPSR1HSD17B10 | |
| SCHEMBL7507189 | 0.94 | RXFP1 (0.31) | ALDH1A1HPGDTSHRNPSR1HSD17B10 | |
| SCHEMBL7463534 | 0.85 | — | — | |
| SCHEMBL7460776 | 0.81 | KDM4E (0.32) | ALDH1A1HPGDTSHRNPSR1HSD17B10 | |
| SCHEMBL6999028 | 0.80 | KMT2A (0.34) | ALDH1A1MAPTDHFR | |
| SCHEMBL6999029 | 0.80 | KMT2A (0.34) | ALDH1A1MAPTDHFR | |
| SCHEMBL7463931 | 0.80 | PIK3R1 (0.34) | — | |
| SCHEMBL7507192 | 0.79 | — | — | |
| SCHEMBL6855392 | 0.79 | MAPT (0.38) | ALDH1A1HPGDTSHRNPSR1HSD17B10 | |
| SCHEMBL6854470 | 0.78 | KMT2A (0.34) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002543199-A | — | — | 2002-12-17 | — | — | JP | claimed |
| EP-1177195-A1 | 1-AMINO TRIAZOLO 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000066584-A1 | 1-AMINO TRIAZOLO¢4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2000-11-09 | — | — | WO | claimed |