Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.57 |
| ▸ | BCR | P11274 | 5/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | PRKCA | P17252 | 4/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKCB | P05771 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PRKCH | P24723 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2081665 | 0.84 | ABL1 (0.70) | ABL1BCRKDRALDH1A1PDGFRA | |
| SCHEMBL7469833 | 0.83 | ABL1 (0.81) | ABL1BCRKDRPDGFRAPRKCA | |
| SCHEMBL14041713 | 0.80 | ABL1 (0.75) | ABL1BCRKDRPDGFRAPRKCA | |
| SCHEMBL1797323 | 0.79 | CYP2A6 (0.64) | ABL1BCRALDH1A1CYP2A6CYP19A1 | |
| SCHEMBL17070834 | 0.78 | ABL1 (0.72) | ABL1BCRKDRPDGFRAPRKCA | |
| SCHEMBL10073332 | 0.77 | CYP2A6 (0.68) | ABL1BCRALDH1A1CYP2A6CYP19A1 | |
| SCHEMBL20402767 | 0.76 | CYP2A6 (0.56) | ABL1BCRALDH1A1CYP2A6CYP19A1 | |
| SCHEMBL206240 | 0.76 | MEN1 (0.73) | ALDH1A1TDP1KMT2ALMNATP53 | |
| SCHEMBL1796850 | 0.76 | CYP2A6 (0.59) | ALDH1A1PRKCACYP2A6CYP19A1KMT2A | |
| SCHEMBL15046260 | 0.76 | CYP2A6 (0.59) | ALDH1A1CYP2A6CYP19A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |