SCHEMBL7464653

SCHEMBL7464653

CCOC(=O)CCCC(=O)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 18/20 0.70
CCR1 P32246 16/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7463924 0.96 CCR3 (0.71) CCR3CCR1
Hydrochloric Acid SCHEMBL7469900 0.95 CCR3 (0.70) CCR3CCR1
SCHEMBL7460099 0.93 CCR3 (0.72) CCR3CCR1
Hydrochloric Acid SCHEMBL7455785 0.93 CCR3 (0.71) CCR3CCR1
SCHEMBL7455839 0.90 CCR3 (0.78) CCR3CCR1
SCHEMBL7459778 0.90 CCR3 (0.74) CCR3CCR1
SCHEMBL7464896 0.89 CCR3 (0.76) CCR3CCR1
Hydrochloric Acid SCHEMBL7471081 0.89 CCR3 (0.65) CCR3CCR1
Hydrochloric Acid SCHEMBL7460233 0.88 CCR3 (0.61) CCR3CCR1
SCHEMBL7467269 0.87 CCR3 (0.68) CCR3CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1219294-A1 MELANIN CONCENTRATING HORMONE ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-03 EP claimed
EP-1219294-A1 MELANIN CONCENTRATING HORMONE ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-03 EP disclosed