Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7469085 | 0.93 | KDM4E (0.36) | KDM4EMAPTPTGDR2RXFP1CHRNA7 | |
| SCHEMBL7461465 | 0.93 | ABCB1 (0.33) | ABCB1HRH4SYK | |
| SCHEMBL6628904 | 0.92 | KDM4E (0.34) | KDM4EMAPTPTGDR2RXFP1CHRNA7 | |
| Hydrochloric Acid SCHEMBL7467807 | 0.92 | FLT3 (0.38) | KDM4EMAPTPTGDR2ABCB1CHRNA7 | |
| SCHEMBL6629514 | 0.91 | KDM4E (0.34) | KDM4EMAPTPTGDR2RXFP1CHRNA7 | |
| SCHEMBL6627643 | 0.91 | KDM4E (0.34) | KDM4EMAPTPTGDR2ABCB1RXFP1 | |
| SCHEMBL6627433 | 0.90 | MAPT (0.38) | KDM4EMAPTPTGDR2ABCB1RXFP1 | |
| SCHEMBL7468511 | 0.90 | HRH4 (0.36) | KDM4EMAPTABCB1HRH4SYK | |
| SCHEMBL8029324 | 0.90 | KDM4E (0.34) | KDM4EMAPTPTGDR2RXFP1CHRNA7 | |
| Hydrochloric Acid SCHEMBL7462551 | 0.89 | FLT3 (0.37) | KDM4EMAPTPTGDR2ABCB1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |