Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.65 |
| ▸ | FNTA | P49354 | 17/20 | 0.62 |
| ▸ | FNTB | P49356 | 17/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7457471 | 0.99 | KCNH2 (0.64) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7452706 | 0.86 | FNTA (0.60) | KCNH2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7455904 | 0.85 | FNTA (0.59) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7937509 | 0.81 | FNTA (0.69) | KCNH2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7939637 | 0.80 | FNTA (0.68) | KCNH2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7939633 | 0.80 | FNTA (0.68) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7939534 | 0.77 | FNTA (1.00) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7927552 | 0.75 | FNTA (1.00) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL8299809 | 0.75 | FNTA (0.54) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7935995 | 0.75 | FNTA (0.76) | KCNH2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891360-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-05-15 | — | — | EP | claimed |
| EP-0891360-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036900-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0891360-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-05-15 | — | — | EP | disclosed |
| US-6001835-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0891360-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036900-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |