Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 8/20 | 0.45 |
| ▸ | CCR1 | P32246 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462251 | 0.96 | MCHR1 (0.82) | MCHR1MEN1KMT2ACCR3CCR1 | |
| SCHEMBL7463098 | 0.91 | MCHR1 (1.00) | MCHR1MEN1KMT2ACCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7463694 | 0.90 | MCHR1 (0.98) | MCHR1MEN1KMT2ACCR3CCR1 | |
| SCHEMBL7459157 | 0.88 | MCHR1 (0.67) | MCHR1MEN1KMT2ACCR3CCR1 | |
| SCHEMBL7467049 | 0.87 | MCHR1 (0.73) | MCHR1MEN1KMT2ACCR3CCR1 | |
| SCHEMBL7463748 | 0.86 | MCHR1 (0.78) | MCHR1MEN1KMT2ACCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7465860 | 0.86 | MCHR1 (0.90) | MCHR1CCR1SIGMAR1F13A1TGM2 | |
| SCHEMBL7462063 | 0.86 | MCHR1 (0.89) | MCHR1CCR3CCR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7461498 | 0.85 | MCHR1 (0.87) | MCHR1CCR3CCR1 | |
| SCHEMBL7470308 | 0.85 | MCHR1 (0.70) | MCHR1MEN1KMT2ACCR3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |